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Women’s Health

Estrogen metabolism is one of the most important factors influencing a women’s health. The majority – 70% – of breast cancer cases are estrogen-induced. Only 10-15% of all cases are due to hereditary gene mutations such as BRCA1 or BRCA2. Understanding a woman’s genomic profile associated with estrogen detoxification can provide personalized strategies to improve

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Depression, Anxiety & Addictions

Mental health issues are a silent epidemic. Drug and alcohol addiction afflicts one in ten Americans. Major depressive disorder and anxiety disorder impact 6–7% of the U.S. population. Emotional health involves complex interactions between an individual’s neurogenetic chemistry and the environment. Contributing factors include neurotransmitter imbalances, mood disorders, inflammation, exaggerated stress response, response to trauma, cognitive flexibility, and

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Personalized Nutrition

What Does My Body Really Need? Certain general guidelines apply to a healthy lifestyle—eat lots of fresh foods, reduce the intake of sugar and processed foods, and drink plenty of water. But any one-size-fits-all dietary program will inevitably fall short of providing the nutritional needs unique to your personal genetic makeup. Humans are 99% genetically identical. It’s

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Healthy Aging

Human longevity is a polygenic trait, meaning multiple genes are responsible for overall health. The Human Genome Project advanced medical science in the understanding of which genes are involved in specific metabolic or disease processes. Genomics has improved our understanding of the aging process and enabled the development of personalized interventions that help people lead longer, healthier, more vibrant and active lives. Environmental

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Athletic Performance

Aerobic Performance, Nutrition, Injury + Recovery People who are physically active tend to live longer. Regular exercise is important for stress reduction, weight management, brain functioning, detoxification, and much more. There are more than 70 genes linked to athletic performance for both the elite athlete as well as the weekend warrior. Genes can impact the risk of

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Cancer Susceptibility

1.5 million people are diagnosed with cancer in the United States every year. By 2020, this number is expected to increase to 2 million, overtaking heart disease as the leading cause of death in America. The National Institute of Health has identified that—without ever being aware of the threat—individuals resist an average of 6–7 cancer

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The Path To Personalized Medicine

This interview with Karen Rider initially appeared in The Progressive Physician. If doctors could magically peer into the genomics of each patient to prescribe the right treatment, at the right time, in the right amount, delivering personalized medicine would be easy as it is effective. Genomic testing and analysis, and translation of that data into

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Heart Disease, High Blood Pressure, Diabetes & Stroke

Heart disease is the leading cause of death for both men and women worldwide, responsible for the deaths of 600,000 American every year. Heart attacks are popularly considered a men’s health issue, but women are just as likely to be affected, and are more likely to die within a year of the attack. For most

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Detoxification

According to the Natural Resources Defense Council, more than 80,000 toxic chemicals have been developed in the last century. And most of them have not been evaluated for their impact on human health. These toxins in our food and the environment can overwhelm the natural detoxification process. When this happens, disease can result. Conditions including

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Genomics and Anxiety: Case Study

A Genomic Medicine Approach to Anxiety Jessica felt helpless, hopeless and alone. She had just turned 18, realizing her dream of living in the big city, yet something was getting in the way. She struggled with worsening anxiety, felt exhausted, was not eating well, and couldn’t focus in school. She felt her dream slipping away,

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Risk Predicting Genomic Models

MTHFR (methylenetetrahydrofolate reductase) is part of the folate pathway implicated in the autism spectrum, neurodevelopmental disorders, mood disorders, cervical dysplasia, cardiovascular disease, several types of cancer, and epigenetic modification of DNA. Genomic research over the last 10 years has primarily focused on MTHFR, however, other genes encoding enzymes downstream from MTHFR in the transmethylation (methyl

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Mental Health–A Systems Approach

How Can Psychiatry Address Biochemical, Nutritional & Neurological Issues?   Functional genomics is an integral part of personalizing approaches to any health condition, including emotional and mental health. Genomic SNPs and brain circuitry abnormalities are linked. Instead of lumping conditions into broad categories such as depression, or ADHD, groupings are being redefined based on underlying genomics,

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Genetics vs. Genomics

Genetics and genomics sound alike and are often used interchangeably, yet important scientific and clinical distinctions exist between these two scientific fields of study. The classical definition of genetics is the study of heredity, how characteristics and traits (phenotypes) of a living organism are transmitted from one generation to the next. This occurs via deoxyribonucleic

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Genomics & Oxidative Stress

Oxidative Stress. A hot topic in helping to address many health issues related to our modern lifestyles. Do you recommend antioxidant supplements for your patients? Which antioxidants are right for them? How much do they need? Can patients get all antioxidants they need from food? How do you know? Genomic testing and analysis is able to answer

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The Truth Behind Cholesterol and Heart Disease

In this second interview with Ric Bratton of This Week In America, Dr. Kline continues the conversation about genomics and health. In this episode, she delves into the myths behind cholesterol and heart disease. She shares the story of a patient who benefited from using genomic testing to reveal the true causes increasing her risk

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